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By Aydin Arici MD and Joshua A. Copel MD

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Additional info for Endocrinology of Pregnancy, An Issue of Obstetrics and Gynecology Clinics (The Clinics: Internal Medicine)

Example text

Trophoblast Res 1991;5: 225 – 80. [37] Nikas G. Endometrial receptivity: changes in cell-surface morphology. Semin Reprod Med 2000;18:229 – 36. [38] Nikas G. Cell surface morphological events relevant to human implantation. Hum Reprod 1999;14(Suppl. 2):37 – 44. [39] Enders AC, Nelson DM. Pinocytotic activity in the uterus of the rat. Am J Anat 1973;138: 277 – 300. [40] Gemzell-Danielsson K, Hamberg M. The effect of antiprogestin (RU486) and prostaglandin biosynthesis inhibitor (naproxen) on uterine fluid prostaglandin F2a concentrations.

PAPP-A levels had a 49% predictive value of fetal demise with a sensitivity of 89% [34]. The association between decreased PAPP-A level and miscarriage is not limited to pregnancies with fetal chromosomal aberrations. 25 multiples of the median (MoM) that were measured between 10 and 13 weeks’ gestation, after excluding fetuses that had chromosome aberrations or anomalies. Other studies that examined the correlation between first trimester PAPP-A levels and adverse fetal outcomes have not produced consistent results.

Stewart CL. Leukemia inhibitory factor and the regulation of pre-implantation development of the mammalian embryo. Mol Reprod Dev 1994;39:233 – 8. Hambartsoumian E. Endometrial leukemia inhibitory factor (LIF) as a possible cause of unexplained infertility and multiple failures of implantation. Am J Reprod Immunol 1998;39: 137 – 43. Giess R, Tanasescu I, Steck T, Sendtner M. Leukemia inhibitory factor gene mutations in infertile women. Mol Hum Reprod 1999;5:581 – 6. Danielsson KG, Swahn ML, Bygdeman M.

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