Download Future Aspects in Contraception: Proceeding of an by B. Runnebaum, T. Rabe, L. Kiesel PDF

By B. Runnebaum, T. Rabe, L. Kiesel

Atrophy of gonadotrophin generating cells Exogenously LH synthesis administered androgens and unlock or anabolic steroids are diminished Prostate Testes general functionality. Testosterone synthesis within the deficit of endogenously Leydig cells is reduced. The synthesized testosterone is exogenously administered compensated for via the steroid isn't in a position to exogenously administered catch up on the deficit of steroid endogenously synthesized testosterone determine 2 Intratesticular and serum testosterone concentrations after remedy with andro­ gens or anabolic steroids so as to replacement for the peripheral androgen deficiency and to accomplish azoospermia. simply because this steroid is alkylated in place 17, poisonous results on liver functionality can't be excluded. Danazol bargains no benefits in comparison with different anabolic steroids; particularly, dangers. various experiments of this sort were played over the last forty or 50 years. the end result in every one case used to be kind of exact: with a undeniable dose of an androgen or anabolic steroid it truly is attainable to inhibit spermatogenesis with out interfering with different androgen-dependent func­ tions, together with libido (potentia coeundi) and accent sexual glands. at the foundation of this pharmacological-endocrinological heritage, androgens and anabolic steroids can be utilized for male fertility keep an eye on, and a number of other medical trials were played over the past 10-15 years. a few of 1 those reviews 2-23 are pointed out in desk 2.

Show description

Read Online or Download Future Aspects in Contraception: Proceeding of an International Symposium held in Heidelberg, 5–8 September 1984 Part 1 Male Contraception PDF

Similar obstetrics & gynecology books

Chesley's Hypertensive Disorders in Pregnancy, 3rd Edition

Hypertensive problems stay one the main motives of maternal and fetal morbidity and loss of life. it's also a number one reason for preterm start referred to now to be a danger think about distant heart problems. regardless of this the hypertensive issues stay marginally studied and administration is usually arguable.

Tumors of the Fetus and Infant: An Atlas

Over the last 20 years, the amazing advances in imaging suggestions, equivalent to ultrasound and quickly or ultra-fast MRI, have ended in the analysis of more and more tumors on the prenatal level. This revised, abundantly illustrated moment variation of Tumors of the Fetus and youngster: An Atlas offers an updated account of the scientific and pathological good points of neoplastic ailment and tumor-like stipulations within the fetus, neonate, and youngster and discusses significant tumor experiences and situations from through the global.

Spontaneous Abortion: Diagnosis and Treatment

16 British experts pool their vast wisdom of spontaneous abortion in a single resource. Their dialogue is at once appropriate to medical occasions and is helping establish components of discussion and replacement tools.

Additional info for Future Aspects in Contraception: Proceeding of an International Symposium held in Heidelberg, 5–8 September 1984 Part 1 Male Contraception

Example text

These compounds are applied in one single injection with a duration of action of 3 and 2 months, respectively. g. endometrium carcinoma in rhesus monkeys) could not be confirmed in large clinical studies. , 1980). Other problems arising from the application of DMPA are bleedings, amenorrhoea and prolonged recurrence of fertility after withdrawal of DMPA. The main reason for the development of new steroidal injectables is the fact that the currently available drugs do not release their substances con- 22 FUTURE ASPECTS IN CONTRACEPTION tinuously.

This new generation of vaginal contraceptives consists of sponges and tampons produced from different materials such as collagen, polyurethane, polyester or cotton. Recent studies have shown that the beta-blocking propranolol can also be used as a locally effective spermatocide. Propranolol has been investigated in its steric as well as in its D-isomeric form and has been proved to be an effective inhibitor of sperm motility. Propranolol is resorbed by the vagina and, in addition, is, in small amounts, secreted by the sperms.

The most important antigens around and in the oocyte are in the follicular fluid, the cumulus oophorus, the corona radiata, the zona pellucida, the membrana vitellina, the oocyte membrane and the oocyte cortex. The specific antibodies against the ovum AN OVERVIEW 43 can prevent oocyte maturation, ovulation, and loosening of the cumulus and the corona, and thereby prevent sperm penetration. Furthermore, they can influence negatively the fixation of the zona pellucida and the membrana vitellina, the passage of the oocyte and of the embryos through the genital tract, and, finally, the repulsion of the zona pellucida and the implantation.

Download PDF sample

Rated 4.28 of 5 – based on 25 votes