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And Roosen-Runge, E. , Atlas of Human Spermatogenesis. Grosse Verlag, Berlin, 1981. 5. , The cycle of the seminiferous epithelium in man, Am. J. , 112:35, 1963. 6. Dym, M. and Fawcett, D. , The blood-testis barrier in the rat and the physiological compartmentation of the seminiferous epithelium, Biol. , 3:308, 1970. 7. Setchell, B. P. and Waites, G. M. , The blood-testis barrier, in Hamilton, D. W. and Greep, R. , Handbook of Physiology, section 7, vol 5. William & Wilkins, Baltimore, 1975, 143.
Pairing, thickening, and shortening of homologous chromosomes denotes the pachytene stage. At an electron microscopic level, structures termed synaptinemal complexes can be seen in the nucleus and represent the pairing mechanism. In the diplotene stage, the paired homologous chromosomes begin to separate as a prelude to the initiation of metaphase. The completion of the first meiotic division results in the formation of two secondary spermatocytes that have the haploid number of chromosomes, each of which is comprised of two chromatids.
6. , spermatogonia, primary spermatocyte, or where spermatids are found in lesser numbers than normal. Should any tubule in the biopsy show the presence of elongating spermatids of the Sd stage of the Clermont classification, then the diagnosis should be hypospermatogenesis. Germ cell arrest. This category is reserved for biopsy appearances wherein spermatogenesis ceases completely at a specific stage of spermatogenesis. Most commonly this is at the primary spermatocyte stage, but may occur at the spermatogonial level or, rarely, at the round spermatid stage.