By Vincenzo Guidetti, George Russell, Matti Sillanpaa, Paul Winner
Fourth writer, Paul Winner, is with ultimate examine Institute, West Palm seashore, FL. Explores the pathophysiology of headache and the issues of prognosis in childrens, particularly the difficulty of communique with children. Emphasizes the significance of support from mom and dad and academics in spotting indicators and triggers. For clinicians.
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Extra info for Headache and Migraine in Childhood and Adolescence
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42. Mauskop A, Altura BT, Cracco RQ, Altura BM, Intravenous magnesium sulfate relieves cluster headaches in patients with low serum ionized magnesium levels. Headache 1995; 35: 597–600. 43. Facchinetti F, Sances G, Borella P, Genazzani 33 NEUROCHEMISTRY 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 34 AR, Nappi G, Magnesium prophylaxis of menstrual migraine: effects on intracellular magnesium. Headache 1991; 31: 298–301. Peikert A, Wilimizig C, Kohne-Volland R, Prophylaxis of migraine with oral magnesium: results from a prospective, multi-center, placebocontrolled and double-blind randomized study.
It is likely that many, if not all, Mg2ϩ functions have a role in migraine mechanisms. Dopamine and migraine Together with 5HT, dopamine also appears to play a crucial role in the mechanism of the migraine attack. In the late 1970s, Sicuteri48 postulated a dopaminergic hypersensitivity in migraine patients and Lance49 pointed out that, as nausea often precedes headache, changes in the brain-stem dopaminergic neurotransmission must be present in migraine. In fact, a variety of prodromal symptoms, including yawning, drowsiness, irritability and hyperactivity, is reported by a signiﬁcant percentage of migraine patients hours or days before the attack onset.