Download Headache and Migraine in Childhood and Adolescence by Vincenzo Guidetti, George Russell, Matti Sillanpaa, Paul PDF

By Vincenzo Guidetti, George Russell, Matti Sillanpaa, Paul Winner

Fourth writer, Paul Winner, is with ultimate examine Institute, West Palm seashore, FL. Explores the pathophysiology of headache and the issues of prognosis in childrens, particularly the difficulty of communique with children. Emphasizes the significance of support from mom and dad and academics in spotting indicators and triggers. For clinicians.

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Extra info for Headache and Migraine in Childhood and Adolescence

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Synapse 1996; 22: 93–9. Hersch SM, Yi H, Heilman CJ, Edwards RH et al, Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra. J Comp Neurol 1997; 388: 211–27. Giros B, Jaber M, Jones SR et al, Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Proc Natl Acad Sci USA 1996; 379: 606–12. Jones SR, Gainetdinov RR, Jaber M et al, Profound neuronal plasticity in response to inactivation of the dopamine transporter.

42. Mauskop A, Altura BT, Cracco RQ, Altura BM, Intravenous magnesium sulfate relieves cluster headaches in patients with low serum ionized magnesium levels. Headache 1995; 35: 597–600. 43. Facchinetti F, Sances G, Borella P, Genazzani 33 NEUROCHEMISTRY 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 34 AR, Nappi G, Magnesium prophylaxis of menstrual migraine: effects on intracellular magnesium. Headache 1991; 31: 298–301. Peikert A, Wilimizig C, Kohne-Volland R, Prophylaxis of migraine with oral magnesium: results from a prospective, multi-center, placebocontrolled and double-blind randomized study.

It is likely that many, if not all, Mg2ϩ functions have a role in migraine mechanisms. Dopamine and migraine Together with 5HT, dopamine also appears to play a crucial role in the mechanism of the migraine attack. In the late 1970s, Sicuteri48 postulated a dopaminergic hypersensitivity in migraine patients and Lance49 pointed out that, as nausea often precedes headache, changes in the brain-stem dopaminergic neurotransmission must be present in migraine. In fact, a variety of prodromal symptoms, including yawning, drowsiness, irritability and hyperactivity, is reported by a significant percentage of migraine patients hours or days before the attack onset.

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