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By Stephen Simpson, Jerome Casas

Advances in Insect body structure publishes eclectic and thematic volumes containing very important, finished and in-depth studies of all elements of insect body structure. it truly is a vital reference resource for invertebrate physiologists and neurobiologists, entomologists, zoologists and bug biochemists. First released in 1963, the serial is now edited through Steve Simpson and Jerome Casas to supply a world standpoint. This thematic quantity on insect integument and color contributes to the revival of insect integrative biology.* Contributions from the prime researchers in entomology * Discusses the physiological range in bugs * comprises in-depth reports with beneficial details for various entomology disciplines

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As b-N-acetylglucosaminidases cut down the accumulation of chitooligosaccharides that are inhibitory to chitinase activity, a synergistic effect is generated by the concurrent dual action of the enzyme systems (Kramer and Muthukrishnan, 2005). , 2007). , 1989). , 2006). Studies with the red flour beetle, T. , 2008). One enzyme (TcNAG1) is the most abundant and knocking down its corresponding transcripts, using RNAi methodology, disrupted the moulting process in all developmental stages resulting in lethal phenotypes.

Although it displayed high similarity to other typical family 18 chitinases, this particular gene does not encode the characteristic serine/threonine-rich linker and the chitin-binding domain. It was speculated that such a truncated gene was an adaptation to entail minimal damage to the PM due to the insect chitin-rich food source. A comprehensive study using RNAi methodology shed light on the in vivo functional specialization of various T. , 2008b). Group I and II chitinases, being associated with moulting, are involved in hydrolysis of cuticular chitin.

1985). Increased activities of enzymes functioning in chitin biosynthesis and hydrolysis were demonstrated in various insects at the organismal, tissue and cellular levels in response to the moulting CHITIN BIOCHEMISTRY: SYNTHESIS, HYDROLYSIS AND INHIBITION 33 hormone. However, chitin metabolism is clearly one aspect of an interconnected complex processes that implicate a sequential cascade activation of a myriadgenes battery. Extensive detailed studies of endocrine control of CS and the hydrolytic endo and exo cleaving enzymes have been carried out.

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