By Phyllis A. Dennery, Giuseppe Buonocore, Ola Didrik Saugstad
This authoritative quantity describes the position of unfastened radicals and antioxidants in prenatal and perinatal issues presently explored in scientific and pre-clinical trials. In twenty-two inclusive chapters, the publication covers the gamut of oxidative rigidity and its relation to various components, together with fertility, metabolism, redox biomarkers, antioxidant security and security, gene polymorphisms, angiogenesis, mobile signaling, mutations and oxidative harm related to lipids, proteins and nucleic acids, membrane trafficking, irritation, mitochondrial disorder, adjustments in immunological functionality, hypoxia, and post-natal stressors. This finished resource will hold clinicians and examine scientists up to date on translational examine into scientific functions. Perinatal and Prenatal Disorders is an important addition to the well known Oxidative tension in utilized easy examine and scientific Practice series.
Read Online or Download Perinatal and Prenatal Disorders PDF
Similar obstetrics & gynecology books
Hypertensive issues stay one the most important reasons of maternal and fetal morbidity and dying. it's also a number one explanation for preterm beginning referred to now to be a chance think about distant heart problems. regardless of this the hypertensive issues stay marginally studied and administration is usually arguable.
Over the last 20 years, the notable advances in imaging concepts, equivalent to ultrasound and speedy or ultra-fast MRI, have resulted in the analysis of more and more tumors on the prenatal degree. This revised, abundantly illustrated moment version of Tumors of the Fetus and baby: An Atlas provides an updated account of the medical and pathological positive aspects of neoplastic illness and tumor-like stipulations within the fetus, neonate, and boy or girl and discusses significant tumor stories and circumstances from in the course of the global.
16 British experts pool their broad wisdom of spontaneous abortion in a single resource. Their dialogue is at once appropriate to scientific occasions and is helping determine components of dialogue and substitute equipment.
- Is Menstruation Obsolete?
- Women's Health: Hormones, Emotions and Behavior (Psychiatry and Medicine)
- Manual Gynäkologische Onkologie
- Surgery for Ovarian Cancer: Principles and Practice, Second Edition
- 100 Cases in Obstetrics and Gynaecology (A Hodder Arnold Publication)
Extra info for Perinatal and Prenatal Disorders
This includes the role of lipid peroxidation products in subsequent reactions with proteins and DNA. More definitive studies of the cross-talk between ROS-mediated signal transduction and DNA oxidation, the latter of which could be considered a form of epigenetic signaling, will likely provide important new insights into the mechanisms of ROS-mediated teratogenesis. Acknowledgment Research from the authors’ laboratory was supported by grants from the Canadian Institutes of Health Research (CIHR).
Birth Defects Res B Dev Reprod Toxicol. 2010;89:124–32. 88. Shapiro AM, Miller L, Wells PG. Breast cancer 1 (BRCA1)-deficient mice develop normally but are more susceptible to ethanol- and methamphetamine-initiated embryopathies (Abstract). Toxicol Sci (supplement: The Toxicologist) 2013;132:213. 89. Shivananjappa MM, Muralidhara. Differential oxidative stress induction and lethality of rat embryos after maternal exposure to t-butyl hydroperoxide during postimplantation period. Drug Chem Toxicol.
1996;6:60–9. 113. Xu DX, Chen YH, Zhao L, Wang H, Wei W. Reactive oxygen species are involved in lipopolysaccharide-induced intrauterine growth restriction and skeletal development retardation in mice. Am J Obstet Gynecol. 2006;195:1707–14. 114. Yu T, Jhun BS, Yoon Y. High-glucose stimulation increases reactive oxygen species production through the calcium and mitogen-activated protein kinase-mediated activation of mitochondrial fission. Antioxid Redox Signal. 2011;14:425–37. 115. Yu WK, Wells PG.